(一)
(二)
(三)
(四)
IL-4 can induce apoptosis in cultured breast cancer cells.
IL-4可以誘導培養的乳腺癌細胞凋亡。
In addition, it has been clarified that IL-4 plays an important role
in the regulation of estrogen synthesis enzymes including 17beta-HSD and 3beta-HSD.
此外,已經闡明IL-4在調節雌激素合成酶(包括17β-HSD和3beta-HSD)中起重要作用。
(五)
In this study,we show that insulin receptor substrate (IRS)-1, IRS-2, and signal transducer
and activator of transcription 6 (STAT6) are phosphorylated following IL-4 treatment
in MCF-7 breast cancer cells.
在這項研究中,我們顯示
在MCF-7乳腺癌細胞中IL-4處理後,胰島素受體底物(IRS)-1,IRS-2和
信號轉導和轉錄激活因子6(STAT6)被磷酸化。
These results suggest STAT6 is required for IL-4-mediated growth inhibition and induction
of apoptosis in human breast cancer cells.
這些結果表明
STAT6是IL-4介導的人乳腺癌細胞生長抑制和誘導凋亡所必需的。
Moreover, these results were supported by the finding that the B- and T-cell signaling cascades
activated by IL-4 or IL-6, respectively, were affected directly by zinc deficiency,
resulting in reduced Stat6 phosphorylation and increased Stat3 phosphorylation.
分別由IL-4或IL-6激活的B細胞和T細胞信號級聯受鋅缺乏直接影響,導致Stat6磷酸化減少和Stat3磷酸化增加。
以上意思是鋅缺乏導致Stat6磷酸化減少,而STAT6又是IL-4介導的人乳腺癌細胞生長抑制和誘導凋亡所必需的,因此鋅有助於乳腺癌細胞凋亡。
鋅可能是讓乳癌細胞死亡的基本物質
【NOW健而婷】高效能鋅配方
不過在查證資料時也有遇到鋅對於乳癌細胞是負面的研究
所以也許
讓癌細胞死亡不能單靠一個物質
應該要廣泛地攝取抗癌食物
才容易全面地壓抑癌細胞的生長
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